The 4400 Center is a fictional building in the science fiction TV series The 4400. According to a postcard in the Season 3 episode "Gone, Part I", the fictional location of the center is 6265 Crescent Road, Seattle, WA. This will become the focal point for the area of Seattle taken over and renamed "Promise City".

The 4400 Center was founded by Jordan Collier as a place where 4400s could take sanctuary and learn to harness their abilities, and where non-4400s could seek out the "inner" 4400 in themselves. A side-effect of non-4400s joining the scheme was that they brought a great deal of money into the center.

The Center and its methods of operation bear a strong and deliberate resemblance to many such institutions of 'enlightenment', including the requirement for a large financial commitment.